Objects : To investigate the effects of Rehmanniae Radix on the blood of rats, the effects of Rehmanniae Radix Preparat(RRP) on serum components was examined.
Methods : Test group of male Sprague-Dawley rats was fed a fructose-rich(25 %; w/w) diet for 5 weeks. During the last 2 weeks the animals was orally administrated with the decoction prepared form RRP. Control group of rats was also fed a fructose-rich diet for 5 weeks, but administrated with saline during the last 2 weeks. Normal group was fed a normal diet for 5 weeks, and administrated with saline. And total cholesterol(Tc), triglyceride(TG), glucose, AST and ALT in serum were measured at 5 weeks on the fructose-rich diet.
Results and Conclusion : The blood levels of Tc, TG, glucose of control group increased, and the activities of AST and ALT of test group decreased compared with those of normal group. The levels of Tc, TG, glucose of teat group decreased, and the activities of AST and ALT of test group increased compared with those of control group. These results suggested that RRP had some regulatory effects on the levels of blood components.
|